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Dioscin alleviates hashimoto’s thyroiditis by regulating the SUMOylation of IRF4 to promote CD4+CD25+Foxp3+ treg cell differentiation

Dioscin has been used as a treatment for Hashimoto’s thyroiditis (HT) in China. However, the molecular mechanisms governing the modes of action of dioscin have not been elucidated. In this study, flow cytometry and Western blotting were used to identify the proportions of CD4+CD25+ regulatory T (Tre...

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Principais autores: Cao Yongjun, Qiao Nan, Sun Yumeng, Jin Xiaowen, Wen Weibo
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2021-01-01
Series:Autoimmunity
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Acceso en liña:http://dx.doi.org/10.1080/08916934.2020.1855428
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