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A phenylalanine at the extracellular side of Kir1.1 facilitates potassium permeation

The Kir1.1 (ROMK) family of weak inward rectifiers controls K secretion in the renal CCT and K recycling in the renal TALH. A single point mutant of the inward rectifier, F127V-Kir1.1b was used to investigate the K transition between the selectivity filter and the outer mouth of the channel. We hypo...

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Autors principals: Henry Sackin, Mikheil Nanazashvili
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2024-12-01
Col·lecció:Channels
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Accés en línia:https://www.tandfonline.com/doi/10.1080/19336950.2023.2294661
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