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Silencing cytokeratin 18 gene inhibits intracellular replication of <it>Trypanosoma cruzi </it>in HeLa cells but not binding and invasion of trypanosomes

<p>Abstract</p> <p>Background</p> <p>As an obligatory intracellular parasite, <it>Trypanosoma cruzi</it>, the etiological agent of Chagas' disease, must invade and multiply within mammalian cells. Cytokeratin 18 (CK18) is among the host molecules that have been suggested as a mediator of important e...

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Bibliografski detalji
Glavni autori: de Mello Samanta M, Curcio Marli, Claser Carla, Silveira Eduardo V, Monteiro Hugo P, Rodrigues Mauricio M
Format: Artigo
Jezik:Inglês
Izdano: BMC 2008-12-01
Serija:BMC Cell Biology
Online pristup:http://www.biomedcentral.com/1471-2121/9/68
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