Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina
The woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) has been included in the transgene cassette of adeno-associated virus (AAV) in several gene therapy clinical trials, including those for inherited retinal diseases. However, the extent to which WPRE increases transgene expre...
Zapisane w:
| Główni autorzy: | , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2017-03-01
|
| Seria: | Molecular Therapy: Nucleic Acids |
| Dostęp online: | http://www.sciencedirect.com/science/article/pii/S2162253116303742 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|