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Efficacy and safety of vesicular monoamine transporter 2 inhibitors for Huntington’s disease chorea based on network meta-analysis

ObjectiveA Bayesian network meta-analysis was conducted to evaluate the efficacy, tolerability, and safety of vesicular monoamine transporter 2 (VMAT2) inhibitors in Huntington’s disease chorea.MethodsThe MEDLINE, Embase, and Cochrane Central Register of Controlled Trials were searched from January...

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Main Authors: Jing Huang, Fei-Fei Chen, Si-Yuan Wen, Pan Tao, Chi Meng, Wei Chen, Chang-Qing Zhou
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2025-09-01
Series:Frontiers in Pharmacology
Subjects:
huntington’s disease
chorea
VMAT2 inhibitors
tetrabenazine
deutetrabenazine
valbenazine
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1637577/full
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