The Ag-195 (C®G) mutation in hereditary persistence of fetal hemoglobin is not associated with activation of a reporter gene in vitro

Hereditary persistence of fetal hemoglobin is an uncommon, benign disorder in which the expression of gamma-globin genes persists into adult life. Several point mutations have been associated with the increased gamma-globin gene promoter activity. We evaluated the -195 (C->G) mutation by a functiona...

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Bibliografische Detailangaben

Hauptverfasser:	Schreiber R., Gonçalves M.S., Junqueira M.L., Saad S.T.O., Krieger J.E., Costa F.F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Associação Brasileira de Divulgação Científica 2001-01-01
Schriftenreihe:	Brazilian Journal of Medical and Biological Research
Schlagworte:	fetal hemoglobin hereditary persistence of fetal hemoglobin HPFH transient expression
Online-Zugang:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000400008
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