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Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data

Abstract Gene set enrichment analysis (GSEA) tools can identify biological insights within gene expression-based studies. Although their statistical performance has been compared, the downstream biological implications that arise when choosing between the range of pairwise or single sample forms of...

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Hlavní autoři: Courtney Bull, Ryan M. Byrne, Natalie C. Fisher, Shania M. Corry, Raheleh Amirkhah, Jessica Edwards, Lily V. S. Hillson, Mark Lawler, Aideen E. Ryan, Felicity Lamrock, Philip D. Dunne, Sudhir B. Malla
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-12-01
Edice:Scientific Reports
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On-line přístup:https://doi.org/10.1038/s41598-024-80534-8
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