OP9 Feeder Cells Are Superior to M2-10B4 Cells for the Generation of Mature and Functional Natural Killer Cells from Umbilical Cord Hematopoietic Progenitors

Adoptive natural killer (NK) cell therapy relies on the acquisition of large numbers of mature and functional NK cells. An option for future immunotherapy treatments is to use large amounts of NK cells derived and differentiated from umbilical cord blood (UCB) CD34+ hematopoietic stem cells (HSCs),...

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Главные авторы:	Lara Herrera, Juan Manuel Salcedo, Silvia Santos, Miguel Ángel Vesga, Francisco Borrego, Cristina Eguizabal
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2017-06-01
Серии:	Frontiers in Immunology
Предметы:	hematopoietic stem cells umbilical cord blood natural killer cells in vitro cell differentiation immunotherapy
Online-ссылка:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00755/full
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