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Mass cytometry reveals immune signatures associated with cytomegalovirus (CMV) control in recipients of allogeneic haemopoietic stem cell transplant and CMV‐specific T cells

Abstract Objectives Cytomegalovirus (CMV) is known to have a significant impact on immune recovery post‐allogeneic haemopoietic stem cell transplant (HSCT). Adoptive therapy with donor‐derived or third‐party virus‐specific T cells (VST) can restore CMV immunity leading to clinical benefit in prevent...

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Principais autores: Helen M McGuire, Simone Rizzetto, Barbara P Withers, Leighton E Clancy, Selmir Avdic, Lauren Stern, Ellis Patrick, Barbara Fazekas de St Groth, Barry Slobedman, David J Gottlieb, Fabio Luciani, Emily Blyth
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2020-01-01
Serier:Clinical & Translational Immunology
Fag:
adoptive T‐cell therapy
CyTOF
haemopoietic stem cell transplant
immune reconstitution
immunotherapy
mass cytometry
Online adgang:https://doi.org/10.1002/cti2.1149
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