Convergent use of RhoGAP toxins by eukaryotic parasites and bacterial pathogens.
Inactivation of host Rho GTPases is a widespread strategy employed by bacterial pathogens to manipulate mammalian cellular functions and avoid immune defenses. Some bacterial toxins mimic eukaryotic Rho GTPase-activating proteins (GAPs) to inactivate mammalian GTPases, probably as a result of evolut...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2007-12-01
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| Colección: | PLoS Pathogens |
| Acceso en línea: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0030203&type=printable |
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