Durable response to nivolumab in combination with regional hyperthermia in a patient with PD-L1-negative metastatic head and neck squamous cell carcinoma

Abstract We report a long-lasting response to the immune checkpoint inhibitor nivolumab in combination with regional hyperthermia (RHT) in a patient with recurrent metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) and negative programmed death ligand 1 (PD-L1) expression. Treatment was well t...

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Hlavní autoři:	Luc M. Berclaz, Anton Burkhard-Meier, Axel Lechner, Michael Völkl, Sinan E. Güler, Sultan Abdel-Rahman, Sina Mansoorian, Wolfgang G. Kunz, Thomas Knösel, Martin Canis, Michael von Bergwelt-Baildon, Rolf D. Issels, Dorit Di Gioia, Lars H. Lindner
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-04-01
Edice:	Cancer Immunology, Immunotherapy
Témata:	Immunotherapy Immune checkpoint inhibitors Head and neck cancer Regional hyperthermia
On-line přístup:	https://doi.org/10.1007/s00262-025-04029-9
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