QR-Code

4,8-Dicarboxyl-8,9-iridoid-1-glycoside inhibits apoptosis in human osteoarthritis chondrocytes via enhanced c-MYC-mediated cholesterol metabolism in vitro

Abstract Background Osteoarthritis (OA) is a degenerative disease related to cholesterol metabolism disorders. However, current therapies for OA are insufficient and no convincing disease-modifying OA drugs exist. Therefore, we aimed to elucidate the mechanism by which borojoa iridoid glycoside (BIG...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: WeiBing Wang, HaiMin Mai, Huang Xu, BaoSheng Jing, CuiYu Yu, XiaoTing Li, DanGui Chen, Yuan Huang, MeiMang Shao, Tao Pan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-12-01
Schriftenreihe:Arthritis Research & Therapy
Schlagworte:
Osteoarthritis
Borojoa
Cholesterol metabolism
Apoptosis
Autophagy
Online-Zugang:https://doi.org/10.1186/s13075-023-03217-1
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge