Effects of Two Boron-Containing Compounds Structurally Related to Topiramate on Three Models of Drug-Induced Seizures in Mice

<b>Background:</b> Epilepsy is a high-burden neurological disorder worldwide, and several sedative drugs are used as therapy. Topiramate is among the more recent drugs shown to be effective in some patients, although its benefits are limited. Two carbohydrate derivatives, FB1 (from D-fructose) and A...

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Autors principals:	Yaqui Valenzuela-Schejtman, Marvin A. Soriano-Ursúa, Elizabeth Estevez-Fregoso, Daniel García-López, R. Ivan Cordova-Chavez, Maricarmen Hernández-Rodríguez, Andrei Biță, Alejandra Contreras-Ramos, Miriam Hernández-Zamora, Eunice D. Farfán-García
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-09-01
Col·lecció:	Pharmaceuticals
Matèries:	boron topiramate seizures neurotoxicity bioactive carbohydrates epilepsy
Accés en línia:	https://www.mdpi.com/1424-8247/18/10/1470
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