c‐Myc–IMPDH1/2 axis promotes tumourigenesis by regulating GTP metabolic reprogramming

Abstract Background Metabolic reprogramming is a hallmark of cancer. Metabolic rate‐limiting enzymes and oncogenic c‐Myc (Myc) play critical roles in metabolic reprogramming to affect tumourigenesis. However, a systematic assessment of metabolic rate‐limiting enzymes and their relationship with Myc...

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Autors principals:	Qiang Zhang, Kaisa Cui, Xiaoya Yang, Qilang He, Jing Yu, Li Yang, Gang Yao, Weiwei Guo, Zhanhao Luo, Yugeng Liu, Yuan Chen, Zhen He, Ping Lan
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2023-01-01
Col·lecció:	Clinical and Translational Medicine
Matèries:	c‐Myc colorectal carcinoma GTP IMPDH1 IMPDH2 metabolic rate‐limiting enzymes
Accés en línia:	https://doi.org/10.1002/ctm2.1164
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