Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity.

Obesity is a major health problem worldwide. We are studying the causes and effects of obesity in C57Bl/6 mice following genetic ablation of NG2, a chondroitin sulfate proteoglycan widely expressed in progenitor cells and also in adipocytes. Although global NG2 ablation delays early postnatal adipog...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Yunchao Chang, Zhi-Gang She, Kenji Sakimura, Amanda Roberts, Karolina Kucharova, David H Rowitch, William B Stallcup
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2012-01-01
Edice:	PLoS ONE
On-line přístup:	https://doi.org/10.1371/journal.pone.0030637
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!