Toll-like receptor 9 is required for opioid-induced microglia apoptosis.

Opioids have been widely applied in clinics as one of the most potent pain relievers for centuries, but their abuse has deleterious physiological effects beyond addiction. However, the underlying mechanism by which microglia in response to opioids remains largely unknown. Here we show that morphine...

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Principais autores:	Lei He, Hui Li, Lin Chen, Junying Miao, Yulin Jiang, Yi Zhang, Zuoxiang Xiao, Gregory Hanley, Yi Li, Xiumei Zhang, Gene LeSage, Ying Peng, Deling Yin
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2011-04-01
叢編:	PLoS ONE
在線閱讀:	http://europepmc.org/articles/PMC3084705?pdf=render
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