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Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse

Crossing over is a critical process during meiosis, although the regulation of this process still remains somewhat elusive. Here, the authors show that PRR19 partners with CNTD1 to enable formation of crossover-specific recombination complexes in mouse germ cells.

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Autori principali: Anastasiia Bondarieva, Kavya Raveendran, Vladyslav Telychko, H. B. D. Prasada Rao, Ramya Ravindranathan, Chrysoula Zorzompokou, Friederike Finsterbusch, Ihsan Dereli, Frantzeskos Papanikos, Daniel Tränkner, Alexander Schleiffer, Ji-Feng Fei, Anna Klimova, Masaru Ito, Dhananjaya S. Kulkarni, Ingo Roeder, Neil Hunter, Attila Tóth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2020-06-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-020-16885-3
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