Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment

Stearoyl-CoA desaturase (SCD) is a microsomal enzyme involved in the biosynthesis of oleate and palmitoleate. Mice with a targeted disruption of the SCD1 isoform (SCD1−/−) exhibit reduced adiposity and increased energy expenditure. To address whether the energy expenditure is attributable to increas...

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Autori principali:	Seong-Ho Lee, Agnieszka Dobrzyn, Pawel Dobrzyn, Shaikh Mizanoor Rahman, Makoto Miyazaki, James M. Ntambi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2004-09-01
Serie:	Journal of Lipid Research
Soggetti:	brown adipose tissue uncoupling protein lipid metabolism
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0022227520312840
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