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Sequential factor delivery enables efficient workflow for universal gene editing in clinical grade iPS cells

Abstract Human induced pluripotent stem cells (iPSCs) are gaining momentum as a powerful starting material in cell therapy. To fully harness their potential, CRISPR technology permits endogenous gene modifications as well as the introduction of advanced features, to increase the immune compatibility...

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Bibliografiset tiedot
Päätekijät: Thomas Berger, Elitsa Borisova, Anna Gamerschlag, Daniel Terheyden-Keighley, Soraia Martins, Boris Greber
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2025-09-01
Sarja:Scientific Reports
Linkit:https://doi.org/10.1038/s41598-025-17876-4
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