A triple-targeting “nano-brake” remodeling the impaired immune microenvironment in skin lesions for psoriasis treatment

Psoriasis, a prevalent immune-mediated chronic inflammatory skin ailment, has been linked to heightened oxidative stress and compromised immune tolerance. Immune checkpoint pathways, particularly the programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) signaling axis, are instrument...

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Detalles Bibliográficos

Principais autores:	Ruijie Chen, Baiqun Duan, Shize Li, Yixuan Zhu, Zihao Huang, Dingchao Shen, Zhanzheng Ye, Yuqi Yan, Chenyu Qiu, Haoxiong Guan, Yinsha Yao, Jie Dong, Fugen Wu, Xinyu Jiang, Xianbao Shi, Longfa Kou
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-06-01
Series:	Materials Today Bio
Assuntos:	Psoriasis Bilirubin ROS PD-1/PDL-1 Th17/Treg
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2590006425004351
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