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Evaluation of Virus-Free Manufacture of Recombinant Proteins Using CRISPR-Mediated Gene Disruption in Baculovirus-Infected Insect Cells

The manufacture and downstream processing of virus-like particles (VLPs) using the baculovirus expression vector system (BEVS) is complicated by the presence of large concentrations of baculovirus particles, which are similar in size and density to VLPs, and consequently are difficult to separate. T...

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Bibliografski detalji
Glavni autori: Mark R. Bruder, Marc G. Aucoin
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2023-01-01
Serija:Vaccines
Teme:
Online pristup:https://www.mdpi.com/2076-393X/11/2/225
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