Tonic Inhibition of Allergic Itch Signaling by the Descending Noradrenergic System in Mice
We investigated whether the descending noradrenergic system regulates allergic itch. Mosquito allergy of the hind paw elicited biting, an itch-related response, in sensitized mice. The biting was inhibited by intrathecal clonidine and reversed by yohimbine, an α2-adrenoceptor antagonist. The biting...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2011-01-01
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| Colección: | Journal of Pharmacological Sciences |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S1347861319307716 |
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