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Whole blood RNA signatures in tuberculosis patients receiving H56:IC31 vaccine as adjunctive therapy

IntroductionTherapeutic vaccination in tuberculosis (TB) represents a Host Directed Therapy strategy which enhances immune responses in order to improve clinical outcomes and shorten TB treatment. Previously, we have shown that the subunit H56:IC31 vaccine induced both humoral and cellular immune re...

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Autori principali: Noelia Alonso-Rodríguez, Eleonora Vianello, Suzanne van Veen, Synne Jenum, Kristian Tonby, Rosalie van Riessen, Xiaoran Lai, Rasmus Mortensen, Tom H. M. Ottenhoff, Anne Ma Dyrhol-Riise
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-02-01
Serie:Frontiers in Immunology
Soggetti:
tuberculosis
H56:IC31 vaccine
host directed therapy
transcriptomics
RNA signature
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1350593/full
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