DNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients

Abstract Background DNA damage response and repair (DDR) genes are crucial for maintaining the integrity of the genome. This study aims to explore the correlation of DDR gene mutations with TMB, clinical characteristics, and outcomes to platinum-based chemotherapy and platinum-based chemotherapy/imm...

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Bibliografski detalji

Glavni autori:	Weiguang Gu, Wenya Zhuang, Mengxia Zhuang, Minhong He, Zhihua Li
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2023-11-01
Serija:	Diagnostic Pathology
Teme:	DDR gene Non-small cell Lung cancer Platinum-based chemotherapy Platinum-based chemotherapy/immunotherapy Metastasis
Online pristup:	https://doi.org/10.1186/s13000-023-01401-0
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