Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease

Cell death and synapse dysfunction are two likely causes of cognitive decline in AD. As cells die and synapses lose their drive, remaining cells suffer an initial decrease in activity. Neuronal homeostatic synaptic scaling then provides a feedback mechanism to restore activity. This homeostatic mec...

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Prif Awduron:	Mark eRowan, Sam eNeymotin, William eLytton
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2014-04-01
Cyfres:	Frontiers in Computational Neuroscience
Pynciau:	Homeostasis Neocortex Alzheimer's disease synaptic scaling neuroprosthetics neuronal networks
Mynediad Ar-lein:	http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00039/full
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