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Identification of a novel bile marker clusterin and a public online prediction platform based on deep learning for cholangiocarcinoma

Abstract Background Cholangiocarcinoma (CCA) is a highly aggressive malignant tumor, and its diagnosis is still a challenge. This study aimed to identify a novel bile marker for CCA diagnosis based on proteomics and establish a diagnostic model with deep learning. Methods A total of 644 subjects (23...

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Principais autores: Long Gao, Yanyan Lin, Ping Yue, Shuyan Li, Yong Zhang, Ningning Mi, Mingzhen Bai, Wenkang Fu, Zhili Xia, Ningzu Jiang, Jie Cao, Man Yang, Yanni Ma, Fanxiang Zhang, Chao Zhang, Joseph W. Leung, Shun He, Jinqiu Yuan, Wenbo Meng, Xun Li
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-08-01
coleção:BMC Medicine
Assuntos:
Cholangiocarcinoma
Clusterin
Deep learning
Diagnostic biomarker
Proteomics
Acesso em linha:https://doi.org/10.1186/s12916-023-02990-9
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