Plasmodium falciparum CRK5 Is Critical for Male Gametogenesis and Infection of the Mosquito

ABSTRACT Cyclin-dependent kinases (CDKs) and cyclins are critical cell cycle regulators in eukaryotes. In this study, we functionally characterized a CDK-related kinase (CRK5) of the human malaria parasite Plasmodium falciparum. P. falciparum CRK5 (PfCRK5) was expressed in asexual blood stages and s...

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Hlavní autoři:	Sudhir Kumar, Olivia R. Gargaro, Stefan H. I. Kappe
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2022-10-01
Edice:	mBio
Témata:	CRK5 gametocyte exflagellation mosquito transmission
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.02227-22
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