TTF-1/p63-Positive Poorly Differentiated NSCLC: A Histogenetic Hypothesis from the Basal Reserve Cell of the Terminal Respiratory Unit

TTF-1 is expressed in the alveolar epithelium and in the basal cells of distal terminal bronchioles. It is considered the most sensitive and specific marker to define the adenocarcinoma arising from the terminal respiratory unit (TRU). TTF-1, CK7, CK5/6, p63 and p40 are useful for typifying the majo...

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Autori principali:	Daniela Cabibi, Sandro Bellavia, Antonino Giulio Giannone, Nadia Barraco, Calogero Cipolla, Anna Martorana, Vito Rodolico, Massimo Cajozzo, Ada Maria Florena
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-01-01
Serie:	Diagnostics
Soggetti:	nsclc non-small-cell lung cancer histogenetic hypothesis ttf-1 p63 basal reserve cells terminal respiratory unit
Accesso online:	https://www.mdpi.com/2075-4418/10/1/25
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