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Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex

Previous studies based on the ‘Quantal Model’ for synaptic transmission suggest that neurotransmitter release is mediated by a single release site at individual synaptic contacts in the neocortex. However, recent studies seem to contradict this hypothesis and indicate that multi-vesicular release (M...

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Principais autores: Natalí Barros-Zulaica, John Rahmon, Giuseppe Chindemi, Rodrigo Perin, Henry Markram, Eilif Muller, Srikanth Ramaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
coleção:Frontiers in Synaptic Neuroscience
Assuntos:
synaptic transmission
quantal analysis
multi vesicular release
neocortex
mathematical model
short-term depression
Acesso em linha:https://www.frontiersin.org/article/10.3389/fnsyn.2019.00029/full
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