MiR-106a-5p in extracellular vesicles derived from alveolar epithelial cells mediates cognitive dysfunction induced by chronic intermittent hypoxia in mice through MAPK signaling pathway

Abstract Background Obstructive sleep apnea (OSA), characterized by chronic intermittent hypoxia (CIH), is frequently associated with cognitive dysfunction. However, the underlying peripheral-central interplay mechanism remains to be elucidated. Recent years have witnessed the proposal of the “lung-...

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Egile Nagusiak:	Bailun Wang, Chang Sun, Ruiqiu Zhang, Angran Gu, Manman Zhao, Xiaobing Zhou, Changping Gu
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2025-12-01
Saila:	Journal of Neuroinflammation
Gaiak:	CIH EVs MiR-106a-5p MAPK Macrophage DUSP2
Sarrera elektronikoa:	https://doi.org/10.1186/s12974-025-03628-8
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