Substituted-Amidine Functionalized Monocyclic β-Lactams: Synthesis and In Vitro Antibacterial Profile

Background. Owing to the intrinsic stability against common β-lactamases and metallo-lactamases, monobactams gathered special attention in antibiotic drug development. However, so far, aztreonam is the only monobactam approved by FDA for clinical use. We designed new derivatives of aztreonam to enha...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Lili He, Lijuan Zhai, Jian Sun, Jingwen Ji, Jinbo Ji, Yuanbai Liu, Yangxiu Mu, Yuanyu Gao, Dong Tang, Rui Jiang, Ko Ko Myo, Zaw Min Thu, Haikang Yang, Zafar Iqbal, Zhixiang Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2021-01-01
Colecção:	Journal of Chemistry
Acesso em linha:	http://dx.doi.org/10.1155/2021/9955206
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!