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Smith-Lemli-Opitz syndrome: A pathophysiological manifestation of the Bloch hypothesis

The biosynthesis of cholesterol, an essential component of higher eukaryotic membranes, was worked out by Konrad Bloch (and Feodor Lynen) in the 1960s and they received the Nobel Prize around that time in recognition of their pioneering contributions. An elegant consequence of this was a hypothesis...

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Autors principals: Amitabha Chattopadhyay, Ashwani Sharma
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2023-01-01
Col·lecció:Frontiers in Molecular Biosciences
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1120373/full
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