Interaction of Macrophages and Cholesterol-Dependent Cytolysins: The Impact on Immune Response and Cellular Survival

Cholesterol-dependent cytolysins (CDCs) are key virulence factors involved in many lethal bacterial infections, including pneumonia, necrotizing soft tissue infections, bacterial meningitis, and miscarriage. Host responses to these diseases involve myeloid cells, especially macrophages. Macrophages...

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Bibliografische Detailangaben

Hauptverfasser:	Roshan Thapa, Sucharit Ray, Peter A. Keyel
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-08-01
Schriftenreihe:	Toxins
Schlagworte:	<i>Streptococcus pyogenes</i> <i>Clostridium perfringens</i> streptolysin O perfringolysin O pore-forming toxin
Online-Zugang:	https://www.mdpi.com/2072-6651/12/9/531
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