The landscape of the prion protein's structural response to mutation revealed by principal component analysis of multiple NMR ensembles.
Prion Proteins (PrP) are among a small number of proteins for which large numbers of NMR ensembles have been resolved for sequence mutants and diverse species. Here, we perform a comprehensive principle components analysis (PCA) on the tertiary structures of PrP globular proteins to discern PrP subd...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2012-01-01
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| Col·lecció: | PLoS Computational Biology |
| Accés en línia: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002646&type=printable |
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