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The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks

Terminally arrested replication forks are restarted through homologous recombination after processing single-stranded DNA gaps. Here the authors show that resection is regulated by the NHEJ factor Ku, helping to fine-tune recombination at forks.

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Autors principals: Ana Teixeira-Silva, Anissia Ait Saada, Julien Hardy, Ismail Iraqui, Marina Charlotte Nocente, Karine Fréon, Sarah A. E. Lambert
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2017-12-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-017-02144-5
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