Targeting mitochondrial autophagy for anti-aging

Abstract Mitochondrial dysfunction is one of the core drivers of aging. It is manifested by reactive oxygen species (ROS) accumulation, mitochondrial DNA (mtDNA) mutations, imbalanced energy metabolism, and abnormal biosynthesis. Mitochondrial autophagy maintains cellular homeostasis by selectively...

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Bibliographic Details

Main Authors:	Wenjun Shan, Yuling Liu, Ruying Tang, Hui Li, Hongjun Yang, Longfei Lin
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2025-12-01
Series:	Cell Death Discovery
Online Access:	https://doi.org/10.1038/s41420-025-02913-y
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