IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis

ABSTRACT Macrophages acquire distinct phenotypes during tissue stress and inflammatory responses. Macrophages are roughly categorized into two different subsets named inflammatory M1 and anti-inflammatory M2 macrophages. We herein identified a unique pathogenic macrophage subpopulation driven by IL-...

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Auteurs principaux:	Yuzhu Hou, Linnan Zhu, Hongling Tian, Hai-Xi Sun, Ruoyu Wang, Lianfeng Zhang, Yong Zhao
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2018-03-01
Collection:	Protein & Cell
Sujets:	interferon-gamma interleukin-17 interleukin-23 imiquimod-induced psoriasis macrophage polarization
Accès en ligne:	http://link.springer.com/article/10.1007/s13238-018-0505-z
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