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Genetic analysis of medaka fish illuminates conserved and divergent roles of Pax6 in vertebrate eye development

Landmark discovery of eye defects caused by Pax6 gene mutations in humans, rodents, and even fruit flies combined with Pax6 gene expression studies in various phyla, led to the master control gene hypothesis postulating that the gene is required almost universally for animal visual system developmen...

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Principais autores: Simona Mikula Mrstakova, Zbynek Kozmik
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cell and Developmental Biology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcell.2024.1448773/full
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