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Signaling Pathway and Transcriptional Regulation in Osteoblasts during Bone Healing: Direct Involvement of Hydroxyapatite as a Biomaterial

Bone defects and periodontal disease are pathological conditions that may become neglected diseases if not treated properly. Hydroxyapatite (HA), along with tricalcium phosphate and bioglass ceramic, is a biomaterial widely applied to orthopedic and dental uses. The in vivo performance of HA is dete...

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Principais autores: Junaidi Khotib, Maria Apriliani Gani, Aniek Setiya Budiatin, Maria Lucia Ardhani Dwi Lestari, Erreza Rahadiansyah, Chrismawan Ardianto
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-06-01
Serier:Pharmaceuticals
Fag:
neglected diseases
osteoblast transcription factors
osteoblast signaling pathway
Runx2
ERK
p38
Online adgang:https://www.mdpi.com/1424-8247/14/7/615
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