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Metabolic alterations in urine extracellular vesicles are associated to prostate cancer pathogenesis and progression

Urine contains extracellular vesicles (EVs) that concentrate molecules and protect them from degradation. Thus, isolation and characterisation of urinary EVs could increase the efficiency of biomarker discovery. We have previously identified proteins and RNAs with differential abundance in urinary E...

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Principais autores: Marc Clos-Garcia, Ana Loizaga-Iriarte, Patricia Zuñiga-Garcia, Pilar Sánchez-Mosquera, Ana Rosa Cortazar, Esperanza González, Verónica Torrano, Cristina Alonso, Miriam Pérez-Cormenzana, Aitziber Ugalde-Olano, Isabel Lacasa-Viscasillas, Azucena Castro, Felix Royo, Miguel Unda, Arkaitz Carracedo, Juan M. Falcón-Pérez
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2018-12-01
coleção:Journal of Extracellular Vesicles
Assuntos:
Prostate
urine
exosomes
metabolomics
metabolism
biomarkers
Acesso em linha:http://dx.doi.org/10.1080/20013078.2018.1470442
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