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Apolipoprotein C3-Rich Low-Density Lipoprotein Induces Endothelial Cell Senescence via FBXO31 and Its Inhibition by Sesamol In Vitro and In Vivo

Premature endothelial senescence decreases the atheroprotective capacity of the arterial endothelium. Apolipoprotein C3 (ApoC3) delays the catabolism of triglyceride-rich particles and plays a critical role in atherosclerosis progression. FBXO31 is required for the intracellular response to DNA dama...

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Bibliografiska uppgifter
Huvudupphov: Ping-Hsuan Tsai, Li-Zhen Chen, Kuo-Feng Tseng, Fang-Yu Chen, Ming-Yi Shen
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2022-04-01
Serie:Biomedicines
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Länkar:https://www.mdpi.com/2227-9059/10/4/854
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