G12/13 signaling in asthma
Abstract Shortening of airway smooth muscle and bronchoconstriction are pathognomonic for asthma. Airway shortening occurs through calcium-dependent activation of myosin light chain kinase, and RhoA-dependent calcium sensitization, which inhibits myosin light chain phosphatase. The mechanism through...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2024-08-01
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| Edice: | Respiratory Research |
| Témata: | |
| On-line přístup: | https://doi.org/10.1186/s12931-024-02920-0 |
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