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Fusobacterium nucleatum infection modulates the transcriptome and epigenome of HCT116 colorectal cancer cells in an oxygen-dependent manner

Abstract Fusobacterium nucleatum, a gram-negative oral bacterium, has been consistently validated as a strong contributor to the progression of several types of cancer, including colorectal (CRC) and pancreatic cancer. While previous in vitro studies have shown that intracellular F. nucleatum enhanc...

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Auteurs principaux: Barath Udayasuryan, Zirui Zhou, Raffae N. Ahmad, Polina Sobol, Chengyu Deng, Tam T. D. Nguyen, Shivanie Kodikalla, Ryan Morrison, Ishan Goswami, Daniel J. Slade, Scott S. Verbridge, Chang Lu
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2024-05-01
Collection:Communications Biology
Accès en ligne:https://doi.org/10.1038/s42003-024-06201-w
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