Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway

Abstract Background Recent studies have shown that both adenosine monophosphate activated protein kinase (AMPK) and the mammalian target of rapamycin (mTOR) are energy sensors and are related to autophagy. Our recent reports have shown that salidroside can exert protective effects against hypoxia-in...

Повний опис

Бібліографічні деталі

Автори:	Di Gui, Zhimin Cui, Lin Zhang, Chang Yu, Dan Yao, Min Xu, Mayun Chen, Peiliang Wu, Guoping Li, Liangxing Wang, Xiaoying Huang
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2017-12-01
Серія:	BMC Pulmonary Medicine
Предмети:	PASMCs Hypoxia Ampk mTOR ULK1 Autophagy
Онлайн доступ:	http://link.springer.com/article/10.1186/s12890-017-0477-4
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!