Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development
Two major ligand-receptor signaling axes – endothelin Edn3 and its receptor Ednrb, and glial-derived neurotrophic factor (GDNF) and its receptor Ret – are required for migration of enteric nervous system (ENS) progenitors to the hindgut. Mutations in either component cause colonic aganglionosis, als...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications Ltd
2024-12-01
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| Serier: | eLife |
| Fag: | |
| Online adgang: | https://elifesciences.org/articles/96424 |
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