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Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase

Mammalian target of rapamycin complex 1 (TORC1) is controlled by the GATOR complex composed of the GATOR1 subcomplex and its inhibitor, the GATOR2 subcomplex, sensitive to amino acid starvation. Previously, we identified fission yeast GATOR1 that prevents deregulated activation of TORC1 (Chia et al....

Celý popis

Uloženo v:
Hlavní autoři: Tomoyuki Fukuda, Fajar Sofyantoro, Yen Teng Tai, Kim Hou Chia, Takato Matsuda, Takaaki Murase, Yuichi Morozumi, Hisashi Tatebe, Tomotake Kanki, Kazuhiro Shiozaki
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications Ltd 2021-02-01
Edice:eLife
Témata:
TORC1
Rag GTPase
GATOR1
GATOR2
Autophagy
Gcn2
On-line přístup:https://elifesciences.org/articles/60969
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