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Exploring chronic and transient tumor hypoxia for predicting the efficacy of hypoxia-activated pro-drugs

Abstract Hypoxia, a low level of oxygen in the tissue, arises due to an imbalance between the vascular oxygen supply and oxygen demand by the surrounding cells. Typically, hypoxia is viewed as a negative marker of patients’ survival, because of its implication in the development of aggressive tumors...

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Autors principals: Shreya Mathur, Shannon Chen, Katarzyna A. Rejniak
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2024-01-01
Col·lecció:npj Systems Biology and Applications
Accés en línia:https://doi.org/10.1038/s41540-023-00327-z
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