Milrinone and levosimendan improve microvascular perfusion in septic rats: a randomized, placebo-controlled trial

Abstract Background Microcirculatory dysfunction is a key pathophysiological feature of sepsis and contributes to organ failure and mortality. In the gastrointestinal tract, impaired barrier function due to microcirculatory injury promotes translocation of inflammatory mediators and bacteria, worsen...

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Principais autores:	Carsten Marcus, Stefan Hof, Alena Gesing, Philisa Thelen, Sarah Orzol, Antonia Vocke, Jan Schulz, Anne Konstanze Charlotte Kuebart, Richard Truse, Christian Vollmer, Inge Bauer, Olaf Picker, Anna Herminghaus
Formato:	Artigo
Idioma:	Inglês
Publicado:	SpringerOpen 2026-03-01
Series:	Intensive Care Medicine Experimental
Assuntos:	Sepsis Microcirculation Inotropic agents Vasopressin Mitochondria Colon
Acceso en liña:	https://doi.org/10.1186/s40635-026-00881-w
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