Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics.

Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to developing a malaria vaccine is the use of proteins located on the sporozoite surface as antigens to elicit...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kristian E Swearingen, Scott E Lindner, Lirong Shi, Melanie J Shears, Anke Harupa, Christine S Hopp, Ashley M Vaughan, Timothy A Springer, Robert L Moritz, Stefan H I Kappe, Photini Sinnis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2016-04-01
Schriftenreihe:	PLoS Pathogens
Online-Zugang:	http://europepmc.org/articles/PMC4851412?pdf=render
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