Mesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer
Abstract Background Ovarian cancer (OC) is characterized by its rapid growth and spread which, accompanied by a low 5-year survival rate, necessitates the development of improved treatments. In ovarian cancer, the selective overexpression of Mucin-16 (MUC16, CA125) in tumor cells highlights its pote...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2024-04-01
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| Schriftenreihe: | Journal of Translational Medicine |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s12967-024-05174-y |
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